Stage 3 Mesothelioma
Stage 3 mesothelioma has spread to the chest wall, food pipe (oesophagus) or lymph nodes on the same side of the chest

Recommended Exposure Limit (REL)
A National Institute for Occupational Safety and Health (NIOSH) time-weighted average (TWA) concentrations for up to a 10-hour workday during a 40-hour workweek.

Chrysotile Asbestos
A fibrous member of the serpentine group of minerals. Chrysotile asbestos fibers are flexible and have a curved morphology. It is the most common form of asbestos used commercially, also referred to as white asbestos.

Pleural effusion
A pleural effusion is an accumulation of fluid between the layers of the membrane that lines the lungs and chest cavity.

Cancer Effect Level (CEL)
The lowest dose of chemical in a study, or group of studies, that produces significant increases in the incidence of cancer (or tumors) between the exposed population and its appropriate control.

Fibrogenic
Causing or contributing to the fibrotic response mechanism in tissues; commonly refers to substances that contribute to fibrosis of the lungs or liver.

Dose-Response Relationship
The quantitative relationship between the amount of exposure to a toxicant and the incidence of the adverse effects.

Stage 1 Mesothelioma
Stage 1 mesothelioma affects one layer of the pleura only. It may have grown into the covering of the heart (pericardium) and the diaphragm

Laparotomy
Abdominal exploration is a type of surgery where the abdomen is opened (laparotomy) and explored (exploratory laparotomy) for examination and treatment of problems. Might be used in relation to asbestos disease problems.

Parenchymal fibrosis
It is easily conceivable that prolonged retention of some types of minerals in the lung would be a stimulating factor for inflammatory and neoplastic processes, leading in turn to parenchymal fibrosis and peripheral cancer.